职    称

 教授

科研方向

 农药加工与施药技术原理，杀菌剂毒理与抗性治理

招生专业

 植物保护（农药学）

联系方式

 18653871817；[email protected]

个人简介

刘峰，男，汉族，山东省临沂市沂水人，无党派人士，农学博士。现任港澳台论坛农药学系主任。泰山产业领军人才，山东省蔬菜产业技术体系-病虫防治与质量控制岗位专家，泉城学者。近年来，主持国家自然科学基金面上项目4项，重点研发计划项目子课题2项。发表研究论文160多篇，其中SCI收录70多篇，授权国家发明及实用新型专利18项，转化1项。开发的阿维菌素、吡唑醚菌酯等农药微囊悬浮剂已产业化生产，获得国家及省部级科技进步奖2项。

教学背景及工作经历

2014.07-至      今：港澳台论坛\教授

1998.09-2001.07：中国农业大学\理学院\农药学专业\博士

1995.09-1998.07：港澳台论坛\植物保护专业\硕士

1988.09-1992.07：港澳台论坛\植物保护专业\学士

教学工作

主要承担本科生《植物化学保护学》、《农药制剂学》，硕士研究生《现代农药研究技术》，博士研究生《农药应用工艺学》等课程的教学，主讲的课程《植物化学保护》入选山东省一流本科课程。

副主编《农药学实验技术与指导》、《农药无公害使用指南》2部，参编《植物化学保护学（第五版）》、《蔬菜农药高效科学施用技术指导手册》、《现代农药剂型加工技术》、《农药制剂学》等专著4部。

指导本科生获得国家SRT计划项目，中国国际大学生创新大赛金奖等多项奖励，个人被评为“第五届山东省优秀研究生指导教师”、“第十一届山东省优秀科技工作者”“山东省优秀创新创业导师”等荣誉称号。

指导硕士、博士研究生获得国家奖学金（4人）、省级优秀学位论文（5篇）、山东省研究生优秀科技创新成果奖（4项）等奖励。

研究方向

1.农药制剂加工技术 以节药、安全为目的研究载药缓控释微/纳米囊制备机理及工业化生产技术；以环境友好为目的研究悬浮剂、水乳剂配制原理及工业化生产技术；以环境安全、增效为目的研究绿色溶剂、表面活性助剂应用技术。

2.农药对靶高效施用技术 研究在施药过程中，理化性质、剂型、助剂以及使用技术等因素影响农药对靶标生物接触、沉积和转移的规律，制定提高农药利用率、降低农药环境风险的调控措施。

3.农药毒理与抗药性风险评估 解析新农药作用机理，研究蔬菜、粮食作物等重要病原菌的抗药性机理、风险评估及治理措施。

4.微生物源农药研究与开发 土壤环境中分离鉴定引起土传病害的根结线虫、镰孢菌等的拮抗菌，进行农药活性成分的解析与生防利用。

科研项目

1.国家自然科学基金面上项目

界面层介导改善与作物叶面互作效能的农药微囊柔性调控机制研究，32272596，2023.01-2026.12

苯基氨基甲酸酯化亲水修饰提高阿维菌素对作物根结线虫病田间防治效果的增效机制，31972293，2020.01-2023.12。

配位组装型农药微胶囊的对靶递释规律及选择毒性调控机制，31772203，2018.01-2021.12。

金属-多酚配合物负载型杀虫微胶囊的成囊机制、释放及杀虫活性调控，31572040，2016.01-2017.12。

2.国家重点研发计划

农药靶向传输释放调控与协同控害技术创新与应用子课题-蔬菜全生育期协同控害的增效技术体系创建，2022YFD1700504，2022-2026

化学农药对靶高效传递与沉积机制及调控子课题-剂型及助剂对叶用和土壤处理农药施用效率的影响及调控途径，2017YFD0200300，2017-2020。

3.国家公益性行业(农业)科研专项

作物根蛆类害虫综合防治技术研究与示范课题-山东设施韭菜等作物根蛆类害虫综合防治技术研究与示范，201303027，2013-2017。

作物孢囊线虫病控制技术研究与示范课题-防治孢囊线虫病新药剂研制及应用，200903040，2009-2013。

农药高效安全科学施用技术子项目-白粉病菌对防治药剂敏感性变异检测及药剂对靶高效沉积技术研发，200903033，2009-2013。

4.山东省重点研发计划(公益类)

速效与持效均衡型农药微囊的研制，2019GNC106099，2019-2021。

5.济南市“泉城学者”建设工程

新型高效除草剂25%硝磺莠去津可分散油悬浮剂的研究开发，2020-2021。

代表性科研成果

1. 论文

2023年度

Tong-fang Jing, Da-xia Zhang, Yao-zhong Zhang, Yan Jin, Xian-zheng Han, Wei Mu, Bei-xing Li*, Feng Liu*. Adsorption behaviour and mechanism of Avermectin-based pesticides in soil driven by H-bonds formed between the compounds and humus. Chemical Engineering Journal, 2023, 459, 141647.

Tao Zhang, Hongzhen Sun, Liyuan Yang, Peng Zhang, Yaozhong Zhang, Jingbo Bai, Feng Liu,* Da-xia Zhang*. Interfacial polymerization depth mediated by the shuttle effect regulating the application performance of pesticide-loaded microcapsules. ACS Nano, 2023, 17(20): 20654-20665.

Tong-fang Jing, Da-xia Zhang, Yan Jin, Guo-dong Si, Bei-xing Li, Wei Mu, Feng Liu*. Humic acid nature and compound structure together determine the capacity of soil to sorb Avermectin B1a and its derivatives. Chemical Engineering Journal, 2023, 453, 139914

Rui Wang, Song Liu, Feng-shou Sun, Xin Yu, Xiao Liu, Bei-xing Li, Wei Mu, Da-xia Zhang*, Feng Liu*. Balance the rapid release of insecticide microcapsules using double-layer shielding effect when the foliar application. Chemical Engineering Journal, 2023, 455, 140899.

Dicheng Ma, Haiyan Yu, Guangrui Cui, Jiamei Zhu, Bingyu Zhu, Wei Mu, Feng Liu⁎. Exposure of zebrafish (Danio rerio) to trans-2- hexenal induces oxidative stress and protein degeneration of the gill. Science of The Total Environment, 2023, 854, 158813.

Chuangling Ren, Guoxian Wang, ChangYang Li, Beixing Li, Wei Mu, Yueming Wu, Feng Liu*. First report of Colletotrichum pandanicola causing crown spot on strawberry in China. Plant Disease, 2023, 107(7): 2238.

Haichao Cao, Yue Chen, Zhigang Qian, Tingjie Huang, Nan Zou, Daxia Zhang, Wei Mu, Beixing Li*, Feng Liu*. Amphiphilicity-driven small alcohols regulate the flexibility of pesticide-loaded microcapsules for better foliar adhesion and utilization. ACS Appl. Mater. Interfaces, 2023, 15, 17, 21444-21456

Yukun Liu, Yujuan Liu, Liyuan Yang, Tao Zhang, Yan Jin, Lihong Liu, Jiang Du, Daxia Zhang, Beixing Li, Chuanjie Gao*, Feng Liu*. The effect of abamectin application in combination with agronomic measures on the control efficacy of cucumber root-knot nematodes and the cucumber yield. Pest Management Science, 2023, 79(9): 3190-3199

Shuai Hu, Xiuhuan Li, Lele Chen, Yueming Wu, Lingtao Meng, Kai Wang, Beixing Li, Feng Liu*. Hexaconazole and binary mixtures of it plus fludioxonil efficiently control tomato leaf mold caused by Cladosporium fulvum. Crop Protection, 2023, 174, 106374.

Dicheng Ma, Tao Zhang, Guoxian Wang, Chong Cao, Wei Mu, Beixing Li, Daolong Dou*, Feng Liu*. Polyurea microcapsule encapsulation improves the contact toxicity, inhibition time and control effect of trans-2-hexenal against Fusarium graminearum. Industrial Crops and Products, 2023, 195, 116463.

2022年度

Haichao Cao, Yue Chen, Daxia Zhang, Yan Jin, Peng Zhang, Beixing Li, Wei Mu, Feng Liu*. Octaphenyl polyoxyethylene regulates the flexibility of pyraclostrobin-loaded soft microcapsules by interfacial polymerization for better foliar adhesion and pesticide utilization. Chemical Engineering Journal, 2022, 439, 135805.

Lifei He, Shuwen Xi, Lei Ding, Beixing Li, Wei Mu, Peiqiang Li*, Feng Liu*. Regulating the entire journey of pesticide application on surfaces of hydrophobic leaves modified by pathogens at different growth stages. ACS Nano, 2022, 16: 1318-1331.

Haojie Gao, Shaokun Shi, Fengxin Luan, Yan Jin, Wenwen Zhang, Yue Xu, Beixing Li, Wei Mu, Chuanjie Gao*, Feng Liu*. Fungicide smoke generated by electrical heating effectively controls gray mold of Chinese chives and reduces residue risk through adequate environmental sterilization. Pest Management Science, 2022, DOI: 10.1002/ps.7312.

Da-xia Zhang, Rui Wang, Chuangling Ren, Yaru Wang, Bei-xing Li, Wei Mu, Feng Liu,* Youming Hou*. One-step construct responsive lignin/polysaccharide/Fe nano loading system driven by digestive enzymes of Lepidopteran for precise delivery of pesticides. ACS applied  materials & interfaces, 2022, 14, 41337-41347.

Jiamei Zhu, Jin Li, Dicheng Ma, Yangyang Gao, Jiagao Cheng, Wei Mu, Beixing Li, Feng Liu*. SDH mutations confer complex cross-resistance patterns to SDHIs in Corynespora cassiicola. Pesticide Biochemistry and Physiology, 2022, 186, 105157.

Dicheng Ma, Guoxian Wang, Jiamei Zhu, Wei Mu, Daolong Dou,* Feng Liu*. Green leaf volatile trans-2-hexenal inhibits the growth of Fusarium graminearum by inducing membrane damage, ROS accumulation, and cell dysfunction. Journal of Agricultural and Food Chemistry, 2022, 70(18): 5646–5657.

Da-xia Zhang, Rui Wang, Haichao Cao, Jian Luo, Tong-fang Jing, Bei-xing Li, Wei Mu, Feng Liu*, Youming Hou*. Emamectin benzoate nanogel suspension constructed from poly(vinyl alcohol)-valine derivatives and lignosulfonate enhanced insecticidal efficacy. Colloids and Surfaces B: Biointerfaces, 2022, 209, 112166.

2021年度

Da-xia Zhang, Jiang Du, Rui Wang, Jian Luo, Tong-fang Jing, Bei-xing Li, Wei Mu, Feng Liu*, Youming Hou*. Core/shell dual-responsive nanocarriers via iron-mineralized electrostatic self-assembly for precise pesticide delivery. Adv. Funct. Mater. 2021, 2102027.

Jian Luo, Yue Gao, Yukun Liu, Xueping Huang, Da-xia Zhang, Haichao Cao, Tongfang Jing, Feng Liu*, Beixing Li*. Self-Assembled degradable nanogels provide foliar affinity and pinning for pesticide delivery by flexibility and adhesiveness adjustment. ACS Nano, 2021, 15, 14598-14609.

Jian Luo, Yue Gao, Yukun Liu, Jiang Du, Da-xia Zhang, Haichao Cao, Tongfang Jing, Bei-xing Li*, Feng Liu*. Using a reactive emulsifier to construct simple and convenient nanocapsules loaded with lambda-cyhalothrin to achieve efficient foliar delivery and insecticidal synergies. Nanoscale, 2021, 13, 15647-15658.

Lifei He, Lei Ding, Beixing Li, Wei Mu, Peiqiang Li*, Feng Liu*. Regulating droplet wetting and pinning behaviors on pathogen-modified hydrophobic surfaces: strategies and working mechanisms. Journal of Agricultural and Food Chemistry, 2021, 69, 11720-11732.

Lifei He, Lei Ding, Beixing Li, Wei Mu, Peiqiang Li, Feng Liu*. Optimization strategy to inhibit droplets rebound on pathogen-modified hydrophobic surfaces. ACS Appl. Mater. Interfaces 2021, 13, 38018- 38028.

Yangyang Gao, Chuangling Ren, Yang Liu, Jiamei Zhu, Beixing Li, Wei Mu, Feng Liu*. Pepper-maize intercropping affects the occurrence of anthracnose in hot pepper. Crop Protection, 2021, 148, 105750.

Kaidi Cui, Lingyan Zhang, Leiming He, Zhengqun Zhang, Tao Zhang, Wei Mu, Jin Lin, Feng Liu*. Toxicological effects of the fungal volatile compound 1-octen-3-ol against the red flour beetle, Tribolium castaneum (Herbst). Ecotoxicology and Environmental Safety, 2021, 208, 111597.

Kaidi Cui, Leiming He, Tongtong Li, Wei Mu, Feng Liu*. Development of boscalid resistance in Botrytis cinerea and an efficient strategy for resistance management. Plant Disease, 2021, 105: 1042-1047.

Kaidi Cui, Leiming He, Yunhe Zhao, Wei Mu, Jin Lin, Feng Liu*. Comparative analysis of Botrytis cinerea in response to the microbial secondary metabolite benzothiazole using iTRAQ-based quantitative proteomics. Phytopathology, 2021, 11(8). DOI: 10.1094/ PHYTO-11- 20-0503-R.

Tongtong Li, Haolin Li, Tingting Liu, Jiamei Zhu, Lanyun Zhang, Wei Mu, Feng Liu*. Evaluation of the antifungal and biochemical activities of mefentrifluconazole against Botrytis cinerea. Pesticide Biochemistry and Physiology, 2021, 173, 104784.

Lifei He, Lei Ding, Peng Zhang, Beixing Li, Wei Mu, Feng Liu*. Impact of the equilibrium relationship between deposition and wettability behavior on the high-efficiency utilization of pesticides. Pest Manag Sci, 2021, 77, 2485-2493.

Kaidi Cui, Leiming He, Guangrui Cui, Tao Zhang, Yue Chen, Tao Zhang, Wei Mu, Feng Liu*. Biological activity of trans-2-hexenal against the storage insect pest Tribolium castaneum (Herbst) and mycotoxigenic storage fungi. Journal of Economic Entomology, 2021, DOI: 10.1093/jee/toab001.

Jiamei Zhu, Xiuhuan Li, Lingyan Zhang, Yangyang Gao, Wei Mu, Feng Liu*. The bioactivity and efficacy of benzovindiflupyr against Corynespora cassiicola, the causal agent of cucumber Corynespora leaf spot. Plant Disease, 2021, DOI: 10.1094/PDIS-11-20-2334-RE.

Dicheng Ma, Song Yang, Jiangong Jiang, Jiamei Zhu, Beixing Li, Wei Mu, Daolong Dou, Feng Liu*. Toxicity, residue and risk assessment of tetraniliprole in soil-earthworm microcosms. Ecotoxicology and Environmental Safety, 2021, 213, 112061.

Lifei He, Lei Ding, Geoffrey I.N. Waterhouse, Beixing Li, Feng Liu*, Peiqiang Li*. Performance matching between the surface structure of cucumber powdery mildew in different growth stages and the properties of surfactant solution. Pest Manag Sci, 2021, 77, 3538-3546.

Xiao-xu Li, Li-fei He, Xiu-yu Pang, Yang-yang Gao, Yang Liu, Peng Zhang, Guang Wei, Wei Mu, Bei-xing Li*, Feng Liu*. Tank-mixing adjuvants enhanced the efficacy of fludioxonil on cucumber anthracnose by ameliorating the penetration ability of active ingredients on target interface. Colloids and Surfaces B: Biointerfaces, 2021, 204, 111804.

Shou-he Pan, Hai-chao Cao, Bei-xing Li*, Da-xia Zhang, Wei Mu, Feng Liu*. Improving the efficacy against crop foliage disease by regulating fungicide adhesion on leaves with soft microcapsules. Pest Manag Sci, 2021, 77, 4418-4424.

2020年度

Jian Luo,# Da-xia Zhang,# Tongfang Jing, Guang Liu, Haichao Cao, Bei-xing Li, Youming Hou, Feng Liu⁎. Pyraclostrobin loaded lignin-modified nanocapsules: Delivery efficiency enhancement in soil improved control efficacy on tomato Fusarium crown and root rot. Chemical Engineering Journal, 2020, 394, 124854.

Tong-fang Jing,# Da-xia Zhang,# Shouhe Pan, Wei Mu, Youming Hou, Feng Liu* . Phenyl isocyanate modified avermectin B1a improves the efficacy against plant-parasitic nematode diseases by facilitating its soil mobility. ACS Sustainable Chem. Eng., 2020, 8, 2310-2319.

Xiao-xu Li, Yang Liu, Li-fei He, Yang-yang Gao, Wei Mu, Peng Zhang, Bei-xing Li,* and Feng Liu*. Fungicide formulations influence their control efficacy by mediating physicochemical properties of spray dilutions and their interaction with target leaves. Journal of Agricultural and Food Chemistry, 2020, 68, 5, 1198-1206.

Jiamei Zhu, Lingyan Zhang, Tongtong Li, Dicheng Ma, Yangyang Gao, Wei Mu, Feng Liu*. Baseline sensitivity of Corynespora cassiicola to metconazole and efficacy of this fungicide. Crop Protection, 2020, 130, 105056.

Leiming He, Kaidi Cui, Yufei Song,Tongtong Li,  Ning Liu, Wei Mu, Feng Liu*. Activity of the novel SDHI fungicide pydiflumetofen against SDHI-sensitive and -resistant isolates of Botrytis cinerea and efficacy against gray mold. Plant Dis. 2020, 104(8): 2168-2173

Xianpeng Zhang, Luxia Zhang, Daxia Zhang, Sisi Liu*, Dengguo Wei*, FengLiu*. Mechanism of the temperature-responsive material regulating porous morphology on epoxy phenolic novolac resin microcapsule surface. Colloids and Surfaces A: Physicochemical and Engineering Aspects, 2020, 593, 124581.

Jiamei Zhu,# Lingyan Zhang,# Hong Li, Yangyang Gao, Wei Mu, Feng Liu*. Development of a LAMP method for detecting the N75S mutant in SDHI-resistant Corynespora cassiicola. Analytical Biochemistry, 2020, 597, 113687.

Kaidi Cui, Leiming He, Zhengqun Zhang, Lingyan Zhang, Wei Mu, Feng Liu*. Effects of benzothiazole on survival for reduced reproduction and development in Tribolium castaneum Herbst (Coleoptera: Tenebrionidae). Pest Management Science, 2020, DOI: 10.1002/ps.5860.

Kaidi Cui, Yunhe Zhao, Leiming He, Jinfeng Ding, Beixing Li, Wei Mu, Feng Liu*. Comparison of transcriptome profiles of the fungus Botrytis cinerea and insect pest. Frontiers in microbiology, 2020, 11, 1043.

Dicheng Ma, Jiangong Jiang, Jiamei Zhu, Lingyan Zhang, Beixing Li, Wei Mu, Feng Liu*. Evaluation of sensitivity and resistance risk of Corynespora cassiicola to isopyrazam and mefentrifluconazole. Plant Disease, 2020, 104(11): 2779-2785.

Da-xia Zhang,# Guang Liu,# Tong-fang Jing, Jian Luo, Guang Wei, Wei Mu, and Feng Liu*. Lignin-modified electronegative epoxy resin nanocarriers effectively deliver pesticides against plant root-knot nematodes (Meloidogyne Incognita). Journal of Agricultural and Food Chemistry, 2020, 68(47): 13562-13572.

2. 专利

1)发明专利

一种多孔型双层囊壁的微胶囊的制备方法ZL201710227728.1（授权日：2022-10-14）

一种核壳结构的载药胶囊的制备方法ZL 202110406404.0（授权日：2022-12-02）

一种糖基化的农药纳米微囊及其制备方法ZL201811622689.6（授权日：2021-12-17）

一种大环内酯类衍生物、其合成及应用ZL201811413890.3(授权日：2021-12-17)

一种含氟啶胺和氯氟醚菌唑的农药组合物ZL202010185295.x(授权日：2021-03-23)

 一种含甲基硫菌灵和氯氟醚菌唑的农药组合物ZL202010185350.5 (授权日：2021-03-23)

环保型农药乳油 ZL201711188706.5(2020-02-18授权)

一种复配熏蒸剂 ZL201610219795.4(2017-12-19授权)

一种具有协同增效作用的三元杀菌和杀线组合物 ZL 201610057887.7(2017-12-08授权)

一种虫螨腈和吡丙醚的杀虫组合物及其制剂与应用ZL2015105202983 (2017-08-04授权)

一种防治马铃薯黑痣病的杀菌组合物 ZL 2015104412503(2017-07-25授权)

一种防治线虫的农药组合物ZL 2015104072766(2017-07-28授权)

一种虫螨腈和新烟碱类杀虫剂的杀虫组合物及其制剂与应用ZL 2015105192905(2017- 04-07授权)

一种微胶囊囊芯释放率的测试方法及装置ZL201510669844.X (2017-03-01授权)

一种含吡丙醚和氟铃脲的农药组合物 ZL201410739317.7 (2016-06-22授权)

一种以单宁酸的金属离子螯合物作为囊壁的农药微胶囊及其制备方法ZL20141 0599573.0(2016-04-27授权)

2)实用新型专利

一种烟剂施药装置 ZL202221100392.5 （授权日：2022-10-04）一种多孔型双层囊壁微胶囊 ZL201720365107.5(2018-04-10授权)

一种多位点滴灌管道 ZL201621323545.7(2017-07-28授权)

一种新型微胶囊 ZL201521092844.X(2016-06-22授权)

一种微胶囊囊芯释放率测试所用装置ZL201520803016.6(2016-02-10授权)